QQ UTG+1 in Ultimate Bet 24+2

I've been catching pretty good cards and I have the big stack at my table with around 4500 chips. I called one shorty's allin for 350 with A10 in the SB and busted his 5s. Only other hands I've shown down were AQ for TPSK and KQ for a split nut straight. Villain has been playing tight/aggressive. He has around 3000 chips. He has taken most of his pots without showdown, but he did gamble it up against a chip spewer with a pair+flush draw. Blinds are 80/160. I open for 480 with QQ in UTG+1 -- standard raise of 3BBs. Villain reraises me 1000 more. This is the first reraise I've seen from him preflop, although others at the table have come over the top preflop with as weak as Q10s and AJo. What should I do?