Any guidelines for playing blind vs blind??

[akvsaq]

Lets say your in SB, everyone folds and you raise w/ say A5o and get called by the BB. Lets say you completely miss but you are against a loose aggressive. You bet flop, he calls and he raises the turn very often. Would you call down?? Also, can anyone give me some guidelines as how to play blind vs blind or blind vs Button where you are the aggressor. When do you give up? If you bet flop, they call, you fire again on the turn??? I'd like to hear some thoughts from you guys. Thank you.