Snapping off a Bluff (5-10 deep stack example)

[aggie]

Villian (5k) is a extremely LAGGISH with bad fundamentals but good instincts and player reading abilities. I have him covered.

4 Limpers to me in the cuttoff and i raise with AsKh. Villian (SB) and 2 of the original limpers call. Villian is getting frustrated with me as i have been making many big preflop raises and punishing limpers. I'm almost certain he called with less than a premium hand

pot (~325)

Flop (2s-4h-5c)

Checked around

Turn 6d (2s-4h-5c)

Villian leads out for 100 and it's folded to me. I have a strong feeling he's bluffing and that i'm ahead. If i call, he's very likely to bluff again on the river (he's likely to bet 200-400 no matter what he has). If i raise, he's very capable of playing back at me if he thinks i'm restealing (which he has seen me do many times before).

What's my move?