Stratgey to get the most out of the calling stations

[tighterr]

6 Max table with two calling stations. First calling station is directly to your left. The second 3 from your left.
What stratgey do you use to get the most out of this? Do you see alot of flops and get more involved or do you play raise and try to isolate when possible?

The problem I have is that with these two callers every pot it changes the odds making it correct to chase alot more and thus causing crazy swings. I am not a fan of the large swings.
Thanks and merry christmas