Sports Betting Theory Question

[TTChamp]

I am a poker player who is getting into sports betting. I follow the NFL and Big East Football closely so those are the areas where I am the most comfortable betting.

Here is my question: why would you ever bet more than one NFL game per week. Shouldn't you just review the schedule and make one big bet on the game you are most confident in?

I understand that betting multiple games can lead to less variance, but the amount I bet on sports is much less than my available bankroll, so variance isn't a major concern for me.