Starting Hands - 6max vs Folded Full Ring

[rid.br]

i've heard sometimes here on 2+2 that if the EP and some MP fold pre-flop in a full ring game, it's the same to ignore them and assume the game is with less players.

I'm not sure about this. I think that maybe the guys on later positions have better odds of having a good starting hand AFTER the early positions all fold.

I'd like to know if my thinking has any sense.

Thank you.