What is the difference tween FAT32 and NTFS???

[cwsiggy]

This is in reference to my new Seagate 160 GB external drive I bought to store music. I was having an issue with it and the guy at Seagate said it is currently formatted for FAT32 which can only handle 4gb transfers at a time?? (not true as I transferred a ton of music way over 4 gb in one swoop no problem. Anyway, should I reformatt the drive for NTFS?? I did notice my other internal 80gb drive are NTFS. What is the diff??

thanks.