Situation I always use a Stop n' Go in.....

[Freudian]

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IMO, you really don't need to get this fancy at a 22.

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I don't really see a stop'n'go as a particularly fancy play. It is simple math. The flop will miss him 2/3 of the time.

Although I prefer to do it if someone limps instead minraises/standardraises. More chance he likes his hand as it is when he raises. And since the standardplay when someone limps with blinds like this is to push, I don't use the stop'n'go all that often. Nor do I think one should.