Preflop 3-betting Theory Questions (3 handed pots)

[mmcd]

Say a slightly LAG player opens in EP or EMP and gets cold-called by a fairly loose player.

Does 3-betting (in position) a bit light have a higher ev here than if the pot were heads up against the opener?

Does 3-betting light here have a higher ev than cold-calling (or folding) with certain types of hands and a lower ev than cold-calling (or folding) with others?

How much more inclined are you to cold-call rather than 3-bet in this spot with marginal hands if you have the button?

Are you more or less inclined to 3-bet if your opponents positions are reversed (i.e. loose players limps and gets raised; assume the loose player will always call the 2 more back to him preflop)?

I have some thoughts about this, but I'm curious to hear what you all think.


Just as a couple of examples of the kinds of situations I'm talking about here:

20/13 opens UTG+1 or UTG+2, 38/10 coldcalls in MP, you have AJo/ATs/KQo/77/66 etc. behind them.
or

20/13 opens in MP and gets cold-called by 38/10 right behind him. You have A8/KJo/KTs/QJ/QTs/JTs/66/55 etc. behind them.