Fashion

[GuyOnTilt]

I'd guess Nike, Gap, and Levi's as all being in the top 5.

GoT

[dblgutshot]

No way the high end designers make the most money.

[lapoker17]

if you count nike, they are the biggest, and dont forget that gap/banana/old navy are all the same company, and nike is still bigger..

[Kyle]

Overall profit or on a per item basis?

Overall profit wise I really doubt anyone can compete with Wal-Mart.

But on a per item basis it is most likely the super high end designers since thier customers are paying such a high premium for the name brand.