When do I go to take a leak?

[RollaJ]

I usually play in a 4-8 game where the blinds are 4-2. In general I will play my blinds, button and CO then go and come back a few hands before the blinds get to me, sometimes I will leave right before my blinds and post after with $2 dead money. I think both can be justified, but wonder which most people think is the better play.... [img]/forums/images/icons/grin.gif[/img]
Does it make a difference if i am at a 2-4 table
Does it make a difference if I take a leak once an hour?