General "lead out on the flop" question

[Isaac Newton]

I'd say you would have to lead out in both cases. You are in great shape after both. You can't play this game thinking that the other guy flopped the nuts every hand. You are in a heads up situation and the flop hit you. Back off only when they let you know that your hand is no good.
Slow play huge hands heads up, not TPTK.