What is cut off point for calling with small PP's

[el_grande]

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How does the number of players effect your decision?

For myself as the number of players (those already in weighed against the potential players that remain to act) increases I like the strength of my PP to increase as well. In other words I won't play a low 22-55 against more than 3 players since even when I do hit the set my chances of winning have decreased. My reasoning here is that more players means more potential for higher sets and it not that then a higher chance someone will pull (or stay for) a straight or flush.

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This sounds very wrong. 1) getting your money in with a set vs. several opponents is very +EV long term, 2) you can control bet sizes in NL so you shouldn't care much about draws. You make bets so calling is a mistake, and a draw semi-bluff is not going to work against a set either.