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[KidPokerX]

huh?
So you know you have the best hand on the turn, yet still bet $150 into a $600 pot in order to induce the OESD to call?
I may not be understanding this, but by doing that you're giving your opponent correct odds to call.
The problem with this question is that you're rarely ever in a decision in which you're 100% sure. You always work with percents ("there's a 60% chance he's on a OESD, 20% chance of overpair, etc.")
Your question is too certain ("what if I know he has an OESD"?). If you're positive he has an OESD (as in you are 100% sure) then I would bet the pot the entire way down - unless you think he'd call for more.
Then, if he does hit I would auto-fold it right to him. See my point?