Laying down trips?

At what point is it right to lay down top trips + top kicker on a paired board? I see players overplaying this hand all too often and losing huge amounts of chips to another player who hit a full house (either with a pocket pair or otherwise)... just the other day I saw AQ checkraise a flop Q 5 Q only to find that his opponent was holding 5 5, another time I saw AK drawn all-in on a flop K K 6 by a player who loose-called K 6 to a pre-flop raise. Top trips + top kicker is a pretty beastly hand when there are no straight or flush draws on the table, but it seems to lose quite a bit... at the same time, folding it to a raise is going to result in getting bluffed out of a lot of big pots. Any advice would be appreciated.