Facing a reraise preflop (PLO8)

[sy_or_bust]

This is a situation where I feel somewhat lost (I have little NL/PL experience in any form of poker). If I'm UTG and limp an A2 hand, I'm not sure how to play against a big MP/LP reraise, especially against a player with PFR btw 7-12. For example:

1) A2s59 limps $1 UTG, 4 callers [$4], Button raises ~$7, blinds fold, Hero??

I've been mucking these situations. I'll play sometimes if I have a good 2-way hand (I don't think suited ace is enough, right?), but I suspect I'm backing off too much.

When is it correct to call/reraise/fold when you can't be sure if the opponent has A23x, AA(2-3)x, AJsAKs, etc.? Do you play the strong low hands with only mediocre/weak high chances? My gut tells me to reraise or fold a vast majority of the time, wanting to kill the positional disadvantage with a strong HU hand (planning to check/fold, pot/fold, or pot/reraise depending on the flop and opponent), and get all-in preflop if necessary.

Thoughts?