How do you play the following offusit hands KJ, QJ, JT, AT, KT and QT pre-flop?

[Prospect]

I think these hands are quite marginal to begin with. So, how do you play the following offsuit hands pre-flop? Do I treat them as big cards or big X-gapped connectors? Would I play them heads-up? Multi-way?

KJ
QJ
JT
AT
KT
QT