To bet or not to bet flopped trips in a multiple raised pot

[SteelheadGLX]

Hero is in the big blind with 44. Preflop raiser on the left, two callers, and then the button makes it 3 to go. All call - 15 small bets.
Flop comes down rainbow Q64, giving our hero a set.

Even though there are likely no draws to fear, I believe you should try and win this large pot immediately. What is the best way to protect the set? Is the correct play to lead out with a bet, or is it to check-raise the reraiser and isolate him?