The psychology of asking your opponent questions during a hand

[ripwalk]

I've read Caro's Book of Tells, but I don't remember anything in it specifically about that topic.

I'm wondering, when faced with a large river bet from your opponent ... Is there any merit to asking your opponent some simple questions about his hand and getting a read on how he reacts/answers?

For example, asking things such as "You have a monster?" "Your hand better than 2 pair?" "Make your flush draw?".... Just stuff like that.

Also, if there is any merit in asking these questions. How should the results be interpreted. If a player remains silent? If a player answers sarcastically or with a joke, if a player answers with a straight face? If a player says "call and find out"?

I'm sure there must be some value in reading your opponents reactions to questions you pose them while in a hand. Any insight would be appreciated.