move from 2/4 to 5/10??? any help

[TimmyJames]

I play fairly profitable poker at the 2/4 level by playing high quality hands, high pairs and AK AQ, hands like that. I am fairly tight and fairly aggresive, and it has done well at that level. I also read the board well, and notice betting patterns from time to time. When I move to 5/10, this doesnt seem to work. What are the big differences between the two levels. Should I play more drawing hands at 5/10? Any input would be great. TY.