Naive Skins Question

If I have an account on a main site, can I open an account on their skins site? For example, if I have an account at pokerroom.com. Can I open a separate account at fullcontact.com, which is a skin of the former? If so, how do I avoid not playing against myself?

[playersare]

generally speaking, you can sign up for as many skins at each network as you want (this is more so the case after Party split off from what is now WPC). the software will either prevent you from opening two "skin" applications at the same time, or it will not allow you to sit at a table where another one of your accounts is already playing.