Yes, I think it's possible. I've been doing it now for the last couple of weeks. Between end of the year paperwork and regular work load, I'll play one or two tables in the background when I'm not extremely busy.

So far, I'm doing fairly well at 2/4 (some full ring and some SH). Might just be good cards, though.


Edited: I get decent reads just from the hands I actually go to the river with. If somebody is out of the ordinary enough to notice, it doesn't take much to make a note of it.