[Catt]

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I don't see how the fact that it is four-handed changes any of these things compared to it being fuller as Catt says (I don't play much fuller anyway if I can avoid it, so I'm not the expert there).

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It doesn't go directly to the points you raised (position, the fact that he may play aggressively) -- it really goes to his opening range. I presume his opening range is quite a bit wider 4-handed than 6-handed when he is first to ask. The poster I was responding to referenced his raising UTG and I guessed that he didn't notice that UTG in this case was really first to act among 4 players. That's all.