Party Poker routinely examines the player's computer in many ways for specific software; it can easily deal fair hands to those players running monitoring packages and cheat everybody else.
Just thought I would share this fine quote in a thread at Winneronline.
The thread is here
If you are bored it is quite funny the theories that are presented, some for the very first time. The best quotes are on page 4 and 5. It is as of now a 6 page thread.
Enjoy.