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In dog breeding it's usually father-daughter...
Don't know if this would be best for humans or not.
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That's very interesting, thankyou. I looked up dog breeding on Wikipedia but it didn't tell me anything.
I did however find this tidbit of info on the Wiki:
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The Rothschilds
Among the descendants of Mayer Amschel Rothschild, the founder of the famous financial and banking family, many of the men married their brothers's daughters or cousins related through the male line.
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I don't know what the genetic effects of an "uncle-niece" offspring are, but perhaps this is the most preferable way for the children in my example to breed? (benkahuna where art thou?)