Let's backtrack through your decisions.

At first glance over the action, I was surprised to see you fold the river. Are you really losing 96.5% of the time here?

Back to the turn. I think you can find a fold to the 3-bet from the CO. Further, I think you can fold the turn for the first bet. I don't think you have more than 3 outs, if even that many, and you will lose more money if the bad outs hit on the river, just because the pot is already so huge.

You have to call that 3-bet on the flop. I don't think you should be raising, though. I really hate raising without a spade in that spot. I get the feeling you raised because you felt you couldn't fold...