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Obviously something that causes a physical addiction (drug) will present differently than a psychological addiction. (sex, gambling etc.)

I'd argue that certain individuals are wired to be addicts. Physical or psychological. Multiple addictions are not uncommon.

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There is a widely-held theory as to a gene that either triggers or allows an addiction. The hardwiring you mention. There is a lot of debate about the psychological side.

The physical damage, some think, leads to the psychological damage. Others think it's just the opposite. But, IMO, given enough time, they'll always be in accompaniment.