I hate these spots.

Most likely villain hands assuming he's not a complete donk: AA, KK, A8, K8, 99, 88, 77, 44, or crap and he's trying to take you off the hand with his stack.

If he is paying any kind of attention he has to have you on either an overpair or a set, or he thinks you are making a move with position. Hmmmmmm.

I think I fold like a wet noodle. You'll have t465 with the blinds about to go to 50/100. I think you have a better chance of stealing/doubling your way to the money then winning this hand.