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If it was a single interviewer then hand write something. It shows more initiative and it gets the potential employer to think about you a day or two after the interview.

More than one interview then send the 'lead' interviewer the hand written note and an email to anyone else you met during the process.

For out of town interviews I have thanked drivers and admins who helped me with accommodations and transportation. Assume that anyone you meet during the interview process has input into the hiring decision.