I didn't know this, but it's kind of funny:
"1. pwned
A corruption of the word "Owned." This originated in an online game called Warcraft, where a map designer misspelled "owned." When the computer beat a player, it was supposed to say, so-and-so "has been owned."
Instead, it said, so-and-so "has been pwned."
It basically means "to own" or to be dominated by an opponent or situation, especially by some god-like or computer-like force.
"Man, I rock at my job, but I still got a bad evaluation. I was pwned."
OR
"That team totally pwned us."
I should have known Warcraft was responsible.
EDIT-
I still love every Warcraft game. Sure, three was kind of disappointing, but still pretty good.
Still, Starcraft remains the pinnacle, IMNSHO.