From the OP's post, I don't necessarily believe he means illicit or illegal drugs. I took him to mean caffeine, nicotine and alcohol, in a nutshell. And if that's where the question is heading, I think he's right.

I think that, in general, a person over the age of 18 in the USA is indulging regularly in at least one of those three things. And that's without taking anything illegal into account. Most adults have some form of substance-based vice, I'd wager.