Since we pretty much only play 22 to catch a set, we are loosing money when we end up playing against for example 2 people in a raised pot.
We are probably making money, due to implied odds, when against at least 3 people in an unraised pot.

I just find that the pots are raised so often that I fold the hand. I mainly play 5/10 at Party and Pacific, but I dont think its that much tighter than 3/6. I could be wrong though :-)