[W. Deranged]

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This a clear preflop mistake. It is a leak. You should stop REGULARLY 3-betting AQo without a read that tells you this player raises junk; even if they are a semi-loose raiser, it is usually a mistake to play this hand. You are behind too many hands that are raised here. what are you hoping? They have a small pocket pair? KQ? AJ? JJ? 1010?; these are the best possible scenerios for you.

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I want others comments on this

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Hellite is right that automatically three-betting AQo is a mistake in general. This sort of scenario is the exact sort of one you should be thinking hard about: getting AQ against a raiser from very early position.

But, again, the major thing you need to realize is that pre-flop play is conditional. Without reads, I'd fold here. On the other hand, I voted that I'd three-bet against the MP1 unknown open-raiser. For me, that slight variation in position swings the decision. But, really, the point is that you should be making these decisions based on your knowledge of your opponents and their playing standards. Thinking in terms of "what is my opponent's range likely to be" and "does AQo hold up well against that range" is the best approach. If, for example, you've seen villain raise hands like KJo, ATo, or 55 in the past, I think three-betting his UTG raise would be correct. If villain is a known LAG or, even better, a maniac, failing to three-bet in this situation would be a big error.