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I don't claim to be a HU expert, but here are some things I have found in HU play:

Information is key. HU play really depends on the type of opponent you are playing and how well you adjust to the situation(s) at hand. The best HU players are tricky, gear changing players who can keep you guessing. This is your goal.

There are very few concrete tips that can be given in HU play. Much of the play is based off reads. The main thing IMO is to adjust according to your opponent's playing style. If he is a LAG, maybe you should c/c more, or call down with more mediocre hands. If he is a calling station, value bet lots more, etc. etc.

Adjust PF requirements accordingly. Use your button as much as possible- unless your opponent will raise frequently from the BB, you should be calling your SB (button) always.

I don't know. HU is almost always read based. It's hard to give tips on such a difficult game.