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If you think you are playing well you should continue, whether you are down 3 buy-ins or up three. Remember it is all one long session!

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Great point, and I actually have a follow-on question. How many hands (how long) should I be playing in one sitting to assume I'm getting a fair run of cards. They say that a deck should be shuffled 7x to guarantee randomness, so is there a generally accepted number of hands one should play in one sitting to try and smooth out really great or really poor cards? Assuming of course that you may leave based on your winning or losing, table conditions, opponents, etc. even if you think cards are going to turn in your favor at some point.

Obviously I probably wouldn't want to go and play for only an hour, but is 3 okay, or is 4 better, or 5?