[pokernicus]

I vote for betting this hand aggressively the whole way (pot-sized bets on flop and turn, and an oversized bet on the river). With a four flush on the board, it's an extreme situation. If he has any reasonable club in his hand, he'll likely call a large bet (he may even call such a bet with a small club in his hand since your bet size might be indicative of a bluff). If he doesn't have a club he'll probably fold even to a very small bet.

The amount you earn during the percentage of times he'll have a club and call a big overbet will outweigh the remaining situations when he'd call a very small bet with no club.