I've made a good amount of money by continuation betting, and I do it almost every time it's heads up.

A couple considerations:
Do you have pokertracker and a HUD? You can simply see your opponents tendencies, and whether or not they are inclined to fold to a flop bet.

MOST importantly, are you potting the flop? My CB's used to be 1/2 pot bets, but I've come to realize that full pot bets command much more respect.

I'd say about 80% of my "grinding" profits come from CB's, and I've been playing the 25's at Party.