Well, in this hand, it's so bad the only way you'd really consider playing it is when everyone is putting money in the pot...and even then, calling two cold w/ complete garbage is still lame.

You've also got to consider how well you play post-flop against this guy meaning you could be making further errors losing even more bets.

Unless UTG+2 is crazy retarded, open-raising by him means you have to have at least something decent. The poster really just give you a nice overlay assuming he's a loose player.