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In a live 1/2 game, a $5 raise will get called in 17 places. Players on the waiting list for 3/6 will run across the room to call your tiny preflop raise despite not having been dealt into the hand because $5 is just too cheap and they will take that price to play the board against you. Raises to $10 or $15 are more likely to be standard and sometimes those will even be called multiple times. In a live 1/2 game with a 50BB stack, I will only fold top pair or better if somebody turns their cards over and they beat me.

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So, you're not laying down TPTK to any big reraise?
What about against players you've read as fairly tight?
What about smaller pots?