Without a read, just fold A-Q preflop to a raise. Even if you happen to have the best hand, you have no way of knowing that. Often times your going to get stuck dumping off a lot of bets with the second best hand (ie, flop is Q-8-3 against KK; A-10-3 against AK; etc.). And when you do make the best hand, you're normally not going to get paid off anyway. The reality is that you're only going to hit an A or Q 1/3 of the time on the flop (and plenty of times you hit your Q and still don't have top pair b/c a K hits, thus the power of A-K, always TPTK if you hit). So 2/3 the time, you have an unimproved A-Q. Even if you have the best hand and the original raiser has K-Jo, what are you going to do when he keeps firing away? Keep calling and praying you're good? So 2/3 the time you're going to miss and probably end up having to let go of it, and 1/3 of the time you're going to hit and be left guessing if you're good or not. Make things easy on yourself and fold to the preflop raise, assuming no reads. This is at best a neutral EV spot, and I suspect it's highly -EV. After all, when you win, you'll probably win a fairly small pot; and when you lose, you lose a big pot. You're not going to be able to outplay too many people at small stakes, so just make it easy on yourself and fold A-Q to the raise.