Are you CO BUTTON MP+1? I have to assume you plan on playing this hand if enough people are in the hand.

I fold this pre-flop. Depending on the action and what I expect the SB and BB to do. I certainly wouldn't try to isolate unless my read says AK and a bet on the flop would make the Villian fold. IF the villian would have to be this passive for me to make this play.