[Ryan Z]

What is the size of the pot? That would help in determining what kind of bet you should make. I'd probably make a bet about the size of the pot, unless it's close to the size of your stack, which then I'd go all in. After all, you have the nuts. You want him to call. You don't make a dime more if he folds. You say the villain is a decent player. I'm assuming you held a pocket pair for your quads? I'd look at it like this then:

1) He was trying to bluff you. You go all in, he folds.

2) He has a full house He raises you enough to get you to call and pay him off (in his mind). He will call your raise, or go all in if he has the best boat possible.

3) He has an overpair for two pair. Unlikely for him to call an all in with the board paired.

I think the only way your all-in works is if he has a full boat. I might err on the side of caution, since you have the nuts. Make a decent sized raise. All in would scare him away in 2 of 3 scenarios. I'm assuming there are no flushes/straights possible. Hope some of this makes sense.