[BottlesOf]

Ok top 3:

1. LOST
2. Rome
3. this is up in the air.... I would put the Wire up top, but season 4 doesn't premiere until '06. So I'll go with "The Daily Show"

I like Invasion, and have heard great things about Nip/Tuck and Prison Break. I think serious consideration can be given to "The Soup" on E!