[johnc]

One of Doyle's favorite hands is 65 because he feels that it's str8 possiblities aren't likely to overlap most of your opponents, assuming they're playing typical high card hands. Also he argues that it would be harder for an opponent to put you on a hand if the boards hits you, even for a gutshot. Given the above discussion, it does make sense (of course this assumes one's postflop skills and reading ability needs either on or close to his level to make these types of hands profitable - I'm not even remotely close!).