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as having pot odds against an opponents range is not enough if they are very aggro and good postflop, conversely ill open my standards up against weaker players who will only be opening with better hands as they easy to read, give free cards etc.

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Isn't that what I said? You're saying you'd choose a range of hands vs a certain opponent. I'm saying the same thing but I have a mathematical foundation for what hands I choose. I'm not about to make a regular habit of defending with 82o just because I think my opponent is weaker.

I'm not sure any one particular player who plays well postflop can get the best of me EVERY time I decide to pick a hand to defend with, regardless of their aggressiveness. Conversely, I'm not saying I'm a professional HU player but I like my chances vs anyone. I ain't skeert.

~stephen