[dmmikkel]

I mean, by only knowing that a person never raises without anything than a big pair and never limps without a lower pair in the early rounds is a huge advantage.

As for one player having an advantage over an equally skilled player thats very possible. Say one plays less tables than the other, or only one of them bothered to study their opponents to a certain degree.

They know just as much about strategy and are equally skilled, yet one has +ev on the other.

Edit: and at 109s and up you just cant avoid pros, but you can work to get an edge on them