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Absent any specific reads and generally assuming we are looking at the typical fishbowl that is Party PLO, do you make that reraise preflop every time?

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Are you also assuming the same ability to get 50% of your stack in pre-flop? If your stack is deeper (and not even that much deeper), then I think you are setting yourself up for some rough times by making that reraise, especially if your reraise is getting 3 or 4 way action.

The whole reason that people say you need to be able to get most of your stack in pre-flop is because when you do, you are most likely going to have the best of it equity-wise. As soon as a majority of your money goes in after the flop jumbles up the equity and the relative strengths of the hands seeing the flop, you become much more likely to be making a mistake by putting that money in.