This is a difficult situation but against most opponents I play with at the middle limits, a fold is usually right. It is too easy for your opponent to have a straight or a set and have you drawing dead. Even against two pair, you may not be getting the right pot odds to chase. One of the reasons it is frequently correct to follow through with a bet on the turn is not only because you believe your hand is best but to find out where your opponent is at in many cases. As an aside, even in those cases where you guess correctly and he is semi-bluffing a draw you will still go on to lose about 20% of the time when he hits at the river. For all these reasons, I think calling is an overall negative EV play against most opponents.


I might call a maniac, a tricky player, or just a novice who is capable of anything but fold against normal people.