Yes, you can obviously figure them out with a program.
http://www.twodimes.net has a relatively simple interface for allowing you to calculate the %age's for as many hands as you like. The long and the short of it, is that it really boils down to memorizing common scenarios. There really aren't that many in hold 'em. PP vs. another PP. Overcard connectors (suited/unsuited) vs. low PP. Two overs vs. two unders. There's obviously deviations for connectors, suited cards, even one pair versus another...but at the end of the day, it's really important to memorize a bunch of these common scenarios. It will give you a surprisingly accurate "guess" the next time two hands are flipped over preflop.