[Bob T.]

What position did you raise in? What position did your opponent three bet in? What are his three betting standards? Do you have any backdoor draws? How have you played in this situation previously in this session? How has your opponent been playing? How do you want him and your other opponents to play against you in future hands?

Probably some more questions also, but if you have the answers to these, then you can start to make a plan for this hand.

Every hand, every situation is a little different, and finding the clues to the little differences and adding them together usually gets you a useful response.